Joined: 15 Aug 2006
Location: 34801 Campus Drive, Fremont, CA 94555
Posted: Tue Nov 14, 2006 3:03 pm Post subject: Melanoma Epitopes Used in Studying Tumor Regression
Melanoma, a malignant tumor that arises in melanocytes, is the most deadly of all skin cancers. Although it accounts for only 4% of all skin cancer cases, melanoma is the leading cause of skin cancer deaths1. Several antigens expressed in melanoma cells and recognized by T cells have been identified and used in developing immunization approaches for tumor regression2. These include: MART-1/Melan-A, gp100, Tyrosinase, p15, TRP-1 and beta-catenin2.
AnaSpec, a leading provider of integrated proteomics solutions, offers a broad collection of peptide products for cancer research, including an extensive listing of melanoma immunodominant epitopes and their analogs.
1. American Cancer Society: Cancer Facts and Figures—2006. Atlanta GA: American Cancer Society, 2006.
2. Rosenberg, SA. J. National Cancer Inst. 88, 1635 (1996). _________________ Ping Yang
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