Press Release Forum [pressreleaseforum.com] Forum Index

Press Release Forum [pressreleaseforum.com]
Free Press Release Distribution

A site of EPR Network

 FAQFAQ   SearchSearch   MemberlistMemberlist   UsergroupsUsergroups   RegisterRegister 
 ProfileProfile   Log in to check your private messagesLog in to check your private messages   Log inLog in 

Real Time Press Release Distribution is here. Try it out, it's free!

 

AnaSpec - Extensive Line of Caspase Substrates & Inhibit

 
Post new topic   Reply to topic    Press Release Forum [pressreleaseforum.com] Forum Index -> Biotech Press Releases
View previous topic :: View next topic  
Author Message
anaspec



Joined: 15 Aug 2006
Posts: 238
Location: 34801 Campus Drive, Fremont, CA 94555

PostPosted: Wed Sep 06, 2006 11:47 am    Post subject: AnaSpec - Extensive Line of Caspase Substrates & Inhibit Reply with quote

Caspases are a family of cysteine-dependent aspartate specific proteases involved in the destruction of cells. In a normal, healthy human being, damaged or mutated cells are regularly destroyed to protect the rest of the body. The induction of caspase-dependent programmed cell death triggers a tightly-controlled cascade of events with the initiator caspases activating effector caspases. These effector caspases not only activate other effector caspases and provide feedback to initiator caspases, they also cleave cellular substrates resulting in morphological changes such as DNA fragmentation, membrane blebbing or apoptotic body formation. These changes, characteristics of apoptosis, ultimately lead to the death of a cell. Caspases, however, may not be the only enzymes involved in cell death; cell death may still occur even if all caspases are all blocked (Reviewed in 1).

Because of their important role in apoptosis and cell signaling, and their identification as drug-screening targets, there is a recognized need for a wide range of caspase substrates and inhibitors. As a leading provider of premium quality peptides and detection reagents, AnaSpec has introduced an extensive list of caspase substrates (including both chromogenic and fluorogenic variations) and caspase inhibitors.

For additional information, visit www.anaspec.com

Reference:
1. Thornberry, NA. and Y. Lazebnik, Science 281, 1312-1316 (1998).
_________________
Ping Yang
Marketing Speialist
34801 Campus Drive
Fremont, CA 94555
1-800-452-5530 (Toll free)
1-510-791-9560 (Tel)
1-510-791-9572 (Fax)
ping@anaspec.com
www.anaspec.com
Back to top
View user's profile Send private message Send e-mail Visit poster's website
Display posts from previous:   
Post new topic   Reply to topic    Press Release Forum [pressreleaseforum.com] Forum Index -> Biotech Press Releases All times are GMT - 4 Hours
Page 1 of 1

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum

Submit Press Release (Free)Submit Press Release