Press Release Forum [pressreleaseforum.com] Forum Index

Press Release Forum [pressreleaseforum.com]
Free Press Release Distribution

A site of EPR Network

 FAQFAQ   SearchSearch   MemberlistMemberlist   UsergroupsUsergroups   RegisterRegister 
 ProfileProfile   Log in to check your private messagesLog in to check your private messages   Log inLog in 

Real Time Press Release Distribution is here. Try it out, it's free!

 

AnaSpec - EnzoLyteTM 520 Renin Assay Kit - Ultra Sensitivity

 
Post new topic   Reply to topic    Press Release Forum [pressreleaseforum.com] Forum Index -> Biotech Press Releases
View previous topic :: View next topic  
Author Message
anaspec



Joined: 15 Aug 2006
Posts: 238
Location: 34801 Campus Drive, Fremont, CA 94555

PostPosted: Mon Jan 08, 2007 4:03 pm    Post subject: AnaSpec - EnzoLyteTM 520 Renin Assay Kit - Ultra Sensitivity Reply with quote

The past decade has witnessed the development of a number of synthetic renin inhibitors1-3. However, increasing demand for accelerated drug discovery and automated inhibitor screening has generated a need for a continuous, homogeneous assay with even greater sensitivity. With the introduction of the ultra-sensitve EnzoLyteTM 520 Renin Assay Kit, AnaSpec now offers a renin assay kit that is 40x more sensitive than comparable kits currently in the market.

Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels, leading to increased blood pressure. Angiotensin II also increases the secretion of ADH and aldosterone, and stimulates the hypothalamus to activate the thirst reflex. Since an overactive renin-angiotensin system leads to hypertension, renin is an attractive target for the treatment of this disease.

While existing renin assay kits offer sub-nanomolar potency and selectivity, AnaSpec’s EnzoLyteTM 520 Renin Assay Kit offers picomolar sensitivity – the highest sensitivity available for commercial renin assay kits.

AnaSpec also offers a shorter emission wavelength kit, EnzoLyte™ 390 Renin Assay Kit -a cost-effective option that offers greater sensitivity than EDANS/DABCYL-based renin assay kits.

EnzoLyte™ 520 Renin Assay Kit
EnzoLyte™ 390 Renin Assay Kit

EnzoLyteTM 520 Renin Assay Kit
FRET pair: 5-FAM/QXLTM520
Ex/Em (nm): 490/520
Min. Detectable Renin Conc. (pM): 2.5
Interference from Autofluorescence: Minimal
Sensitivity: Ultra-sensitive

EnzoLyteTM 390 Renin Assay Kit
FRET pair: Mc-Ala/Dnp
Ex/Em (nm): 330/390
Min. Detectable Renin Conc. (pM): 25
Interference from Autofluorescence: High
Sensitivity: Good

Company B
FRET pair:EDANS/DABCYL
Ex/Em (nm): 335/495
Min. Detectable Renin Conc. (pM):100
Interference from Autofluorescence:High
Sensitivity:Minimal

For more information, visit www.anaspec.com

AnaSpec, Inc., located in San Jose, CA, is a leading provider of integrated proteomics solutions to pharmaceutical, biotech, and academic research institutions throughout the world. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents, and combinatorial chemistry.
_________________
Ping Yang
Marketing Speialist
34801 Campus Drive
Fremont, CA 94555
1-800-452-5530 (Toll free)
1-510-791-9560 (Tel)
1-510-791-9572 (Fax)
ping@anaspec.com
www.anaspec.com
Back to top
View user's profile Send private message Send e-mail Visit poster's website
Display posts from previous:   
Post new topic   Reply to topic    Press Release Forum [pressreleaseforum.com] Forum Index -> Biotech Press Releases All times are GMT - 4 Hours
Page 1 of 1

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum

Submit Press Release (Free)Submit Press Release